<SEC-DOCUMENT>0001193125-22-037080-index.html : 20220211
<SEC-HEADER>0001193125-22-037080.hdr.sgml : 20220211
<ACCEPTANCE-DATETIME>20220211161751
ACCESSION NUMBER:		0001193125-22-037080
CONFORMED SUBMISSION TYPE:	SC 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20220211
DATE AS OF CHANGE:		20220211
GROUP MEMBERS:		ABG MANAGEMENT LTD.
GROUP MEMBERS:		ALLY BRIDGE GROUP (NY) LLC
GROUP MEMBERS:		ALLY BRIDGE MEDALPHA MANAGEMENT GP, LLC
GROUP MEMBERS:		ALLY BRIDGE MEDALPHA MANAGEMENT L.P.
GROUP MEMBERS:		FAN YU

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Syros Pharmaceuticals, Inc.
		CENTRAL INDEX KEY:			0001556263
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				453772460
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-89552
		FILM NUMBER:		22621224

	BUSINESS ADDRESS:	
		STREET 1:		35 CAMBRIDGE PARK DRIVE
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02140
		BUSINESS PHONE:		617-744-1340

	MAIL ADDRESS:	
		STREET 1:		35 CAMBRIDGE PARK DRIVE
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02140

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	LS22, Inc.
		DATE OF NAME CHANGE:	20120815

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Ally Bridge MedAlpha Master Fund L.P.
		CENTRAL INDEX KEY:			0001831963
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			E9
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		15 QUEENS ROAD CENTRAL, UNIT 3002-3004
		STREET 2:		30TH FLOOR, GLOUCESTER TWR, THE LANDMARK
		CITY:			HONG KONG
		STATE:			F4
		ZIP:			0000000000
		BUSINESS PHONE:		852 31219699

	MAIL ADDRESS:	
		STREET 1:		15 QUEENS ROAD CENTRAL, UNIT 3002-3004
		STREET 2:		30TH FLOOR, GLOUCESTER TWR, THE LANDMARK
		CITY:			HONG KONG
		STATE:			F4
		ZIP:			0000000000
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G/A
<SEQUENCE>1
<FILENAME>d296826dsc13ga.htm
<DESCRIPTION>SC 13G/A
<TEXT>
Document 1 - file: d296826dsc13ga.htm

</DOCUMENT>
</SEC-DOCUMENT>