<SEC-DOCUMENT>0001104659-20-021152-index.html : 20200214
<SEC-HEADER>0001104659-20-021152.hdr.sgml : 20200214
<ACCEPTANCE-DATETIME>20200214114309
ACCESSION NUMBER:		0001104659-20-021152
CONFORMED SUBMISSION TYPE:	SC 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20200214
DATE AS OF CHANGE:		20200214

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Syros Pharmaceuticals, Inc.
		CENTRAL INDEX KEY:			0001556263
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				453772460
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-89552
		FILM NUMBER:		20616116

	BUSINESS ADDRESS:	
		STREET 1:		35 CAMBRIDGE PARK DRIVE
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02140
		BUSINESS PHONE:		617-744-1340

	MAIL ADDRESS:	
		STREET 1:		35 CAMBRIDGE PARK DRIVE
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02140

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	LS22, Inc.
		DATE OF NAME CHANGE:	20120815

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ARK Investment Management LLC
		CENTRAL INDEX KEY:			0001697748
		IRS NUMBER:				464309299
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		3 EAST 28TH STREET, 7TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10016
		BUSINESS PHONE:		212-426-7040

	MAIL ADDRESS:	
		STREET 1:		3 EAST 28TH STREET, 7TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10016
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G/A
<SEQUENCE>1
<FILENAME>tm208047d7_sc13ga.htm
<DESCRIPTION>SC 13G/A
<TEXT>
Document 1 - file: tm208047d7_sc13ga.htm

</DOCUMENT>
</SEC-DOCUMENT>