<SEC-DOCUMENT>0001104659-16-145304-index.html : 20160919
<SEC-HEADER>0001104659-16-145304.hdr.sgml : 20160919
<ACCEPTANCE-DATETIME>20160919065636
ACCESSION NUMBER:		0001104659-16-145304
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20160915
FILED AS OF DATE:		20160919
DATE AS OF CHANGE:		20160919

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Syros Pharmaceuticals, Inc.
		CENTRAL INDEX KEY:			0001556263
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				453772460
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		480 ARSENAL STREET
		STREET 2:		SUITE 130
		CITY:			WATERTOWN
		STATE:			MA
		ZIP:			02472
		BUSINESS PHONE:		617-744-1340

	MAIL ADDRESS:	
		STREET 1:		480 ARSENAL STREET
		STREET 2:		SUITE 130
		CITY:			WATERTOWN
		STATE:			MA
		ZIP:			02472

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	LS22, Inc.
		DATE OF NAME CHANGE:	20120815

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			SHARP PHILIP A
		CENTRAL INDEX KEY:			0001226295
		STATE OF INCORPORATION:			MA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37813
		FILM NUMBER:		161890707

	MAIL ADDRESS:	
		STREET 1:		BIOGEN INC LEGAL DEPARTMENT
		STREET 2:		14 CAMBRIDGE CENTER
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>a4.xml
<DESCRIPTION>4
<TEXT>
Document 1 - file: a4.html

Document 1 - RAW XML: a4.xml

</DOCUMENT>
</SEC-DOCUMENT>