<SEC-DOCUMENT>0001104659-16-131410-index.html : 20160707
<SEC-HEADER>0001104659-16-131410.hdr.sgml : 20160707
<ACCEPTANCE-DATETIME>20160707060316
ACCESSION NUMBER:		0001104659-16-131410
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20160706
FILED AS OF DATE:		20160707
DATE AS OF CHANGE:		20160707

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Syros Pharmaceuticals, Inc.
		CENTRAL INDEX KEY:			0001556263
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				453772460
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		480 ARSENAL STREET
		STREET 2:		SUITE 130
		CITY:			WATERTOWN
		STATE:			MA
		ZIP:			02472
		BUSINESS PHONE:		617-744-1340

	MAIL ADDRESS:	
		STREET 1:		480 ARSENAL STREET
		STREET 2:		SUITE 130
		CITY:			WATERTOWN
		STATE:			MA
		ZIP:			02472

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	LS22, Inc.
		DATE OF NAME CHANGE:	20120815

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Green Jeremy
		CENTRAL INDEX KEY:			0001650527

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37813
		FILM NUMBER:		161755488

	MAIL ADDRESS:	
		STREET 1:		ONE LETTERMAN DRIVE, BUILDING D
		STREET 2:		SUITE D3-300
		CITY:			SAN FRANCISCO
		STATE:			CA
		ZIP:			94129

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Redmile Group, LLC
		CENTRAL INDEX KEY:			0001425738
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37813
		FILM NUMBER:		161755489

	BUSINESS ADDRESS:	
		STREET 1:		ONE LETTERMAN DRIVE
		STREET 2:		BUILDING D, SUITE D3-300
		CITY:			SAN FRANCISCO
		STATE:			CA
		ZIP:			94129
		BUSINESS PHONE:		415-489-9980

	MAIL ADDRESS:	
		STREET 1:		ONE LETTERMAN DRIVE
		STREET 2:		BUILDING D, SUITE D3-300
		CITY:			SAN FRANCISCO
		STATE:			CA
		ZIP:			94129
</SEC-HEADER>
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<TYPE>4
<SEQUENCE>1
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<TEXT>
Document 1 - file: a4.html

Document 1 - RAW XML: a4.xml

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</SEC-DOCUMENT>