<SEC-DOCUMENT>0000919574-25-001367-index.html : 20250214
<SEC-HEADER>0000919574-25-001367.hdr.sgml : 20250214
<ACCEPTANCE-DATETIME>20250214101024
ACCESSION NUMBER:		0000919574-25-001367
CONFORMED SUBMISSION TYPE:	SCHEDULE 13G/A
PUBLIC DOCUMENT COUNT:		2
FILED AS OF DATE:		20250214
DATE AS OF CHANGE:		20250214

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Syros Pharmaceuticals, Inc.
		CENTRAL INDEX KEY:			0001556263
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				453772460
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-89552
		FILM NUMBER:		25624375

	BUSINESS ADDRESS:	
		STREET 1:		35 CAMBRIDGE PARK DRIVE
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02140
		BUSINESS PHONE:		617-744-1340

	MAIL ADDRESS:	
		STREET 1:		35 CAMBRIDGE PARK DRIVE
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02140

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	LS22, Inc.
		DATE OF NAME CHANGE:	20120815

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Avidity Partners Management LP
		CENTRAL INDEX KEY:			0001791827
		ORGANIZATION NAME:           	
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		2828 N HARWOOD STREET
		STREET 2:		SUITE 1220
		CITY:			DALLAS
		STATE:			TX
		ZIP:			75201
		BUSINESS PHONE:		214-550-1822

	MAIL ADDRESS:	
		STREET 1:		2828 N HARWOOD STREET
		STREET 2:		SUITE 1220
		CITY:			DALLAS
		STATE:			TX
		ZIP:			75201
</SEC-HEADER>
<DOCUMENT>
<TYPE>SCHEDULE 13G/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
Document 1 - file: primary_doc.html

Document 1 - RAW XML: primary_doc.xml

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99
<SEQUENCE>2
<FILENAME>d11606712_ex99-a.htm
<TEXT>
Document 2 - file: d11606712_ex99-a.htm

</DOCUMENT>
</SEC-DOCUMENT>