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ACCESSION NUMBER:		0000912057-16-000560
CONFORMED SUBMISSION TYPE:	DRS/A
PUBLIC DOCUMENT COUNT:		19
FILED AS OF DATE:		20160419
<PUBLIC-REL-DATE>20160603
DATE AS OF CHANGE:		20160425

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Syros Pharmaceuticals, Inc.
		CENTRAL INDEX KEY:			0001556263
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				453772460
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		DRS/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	377-01218
		FILM NUMBER:		161577711

	BUSINESS ADDRESS:	
		STREET 1:		480 ARSENAL STREET
		STREET 2:		SUITE 130
		CITY:			WATERTOWN
		STATE:			MA
		ZIP:			02472
		BUSINESS PHONE:		617-744-1340

	MAIL ADDRESS:	
		STREET 1:		480 ARSENAL STREET
		STREET 2:		SUITE 130
		CITY:			WATERTOWN
		STATE:			MA
		ZIP:			02472

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	LS22, Inc.
		DATE OF NAME CHANGE:	20120815
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