Revenue - Revenue by Species (Details) - USD ($) $ in Millions	3 Months Ended		6 Months Ended
	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022
Revenue from External Customer [Line Items]
Revenue	$ 2,180	$ 2,052	$ 4,180	$ 4,038
Contract manufacturing & human health
Revenue from External Customer [Line Items]
Revenue	20	18	37	36
Dogs and Cats
Revenue from External Customer [Line Items]
Revenue	1,424	1,303	2,577	2,502
Horses
Revenue from External Customer [Line Items]
Revenue	65	63	137	127
Cattle
Revenue from External Customer [Line Items]
Revenue	329	328	728	692
Swine
Revenue from External Customer [Line Items]
Revenue	133	144	275	298
Poultry
Revenue from External Customer [Line Items]
Revenue	131	121	270	245
Fish
Revenue from External Customer [Line Items]
Revenue	52	47	101	91
Sheep and other
Revenue from External Customer [Line Items]
Revenue	26	28	55	47
Livestock
Revenue from External Customer [Line Items]
Revenue	671	668	1,429	1,373
Companion animal
Revenue from External Customer [Line Items]
Revenue	1,489	1,366	2,714	2,629
Other pharmaceuticals
Revenue from External Customer [Line Items]
Revenue	$ 315	$ 265	$ 609	$ 519