Revenue - Revenue by Major Species (Details) - USD ($) $ in Millions	3 Months Ended		6 Months Ended
	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023		Jun. 30, 2022
Revenue from External Customer [Line Items]
Revenue	$ 2,180	$ 2,052	$ 4,180		$ 4,038
Contract manufacturing & human health
Revenue from External Customer [Line Items]
Revenue	20	18	37		36
Companion animal
Revenue from External Customer [Line Items]
Revenue	1,489	1,366	2,714		2,629
Companion animal | U.S.
Revenue from External Customer [Line Items]
Revenue	959	895	1,680		1,669
Companion animal | International
Revenue from External Customer [Line Items]
Revenue	530	471	1,034		960
Livestock
Revenue from External Customer [Line Items]
Revenue	671	668	1,429		1,373
Livestock | U.S.
Revenue from External Customer [Line Items]
Revenue	206	196	490		442
Livestock | International
Revenue from External Customer [Line Items]
Revenue	465	472	939		931
Operating Segments | U.S.
Revenue from External Customer [Line Items]
Revenue	1,165	1,091	2,170		2,111
Operating Segments | International
Revenue from External Customer [Line Items]
Revenue	$ 995	$ 943	$ 1,973	[1]	$ 1,891	[1]

[1] Revenue denominated in euros was $421 million and $407 million for the six months ended June 30, 2023 and 2022, respectively.