Revenue - Revenue by Major Species (Details) - USD ($) $ in Millions		3 Months Ended
		Mar. 31, 2023	Mar. 31, 2022
Revenue from External Customer [Line Items]
Revenue		$ 2,000	$ 1,986
Contract manufacturing & human health
Revenue from External Customer [Line Items]
Revenue		17	18
Companion animal
Revenue from External Customer [Line Items]
Revenue		1,225	1,263
Companion animal | U.S.
Revenue from External Customer [Line Items]
Revenue		721	774
Companion animal | International
Revenue from External Customer [Line Items]
Revenue		504	489
Livestock
Revenue from External Customer [Line Items]
Revenue		758	705
Livestock | U.S.
Revenue from External Customer [Line Items]
Revenue		284	246
Livestock | International
Revenue from External Customer [Line Items]
Revenue		474	459
Operating Segments | U.S.
Revenue from External Customer [Line Items]
Revenue		1,005	1,020
Operating Segments | International
Revenue from External Customer [Line Items]
Revenue	[1]	$ 978	$ 948

[1] Revenue denominated in euros was $204 million and $203 million for the three months ended March 31, 2023 and 2022, respectively.