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Share-Based Payments (Stock option activity) (Details) - USD ($)
$ / shares in Units, $ in Millions
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Shares      
Outstanding, Beginning Balance (in shares) 2,132,567    
Granted (in shares) 235,900    
Exercised (in shares) (263,174)    
Forfeited (in shares) (37,687)    
Outstanding, Ending Balance (in shares) 2,067,606 2,132,567  
Weighted-average Exercise Price Per Share      
Outstanding, Beginning Balance (in dollars per share) $ 80.19    
Granted (in dollars per share) 201.23    
Exercised (in dollars per share) 57.10    
Forfeited (in dollars per share) 168.69    
Outstanding, Ending Balance (in dollars per share) $ 95.32 $ 80.19  
Outstanding, Weighted-average Remaining Contractual Term (in years) 5 years    
Outstanding, Aggregate Intrinsic Value [1] $ 122    
Exercisable, December 31, 2022 1,317,387    
Exercisable, Weighted Average Exercise Price Per Share $ 54.48    
Exercisable, Weighted Average Remaining Contractual Term (in years) 3 years 3 months 18 days    
Vested and expected to vest, Aggregate Intrinsic Value [1] $ 121    
Weighted-average grant date fair value per stock option $ 51.13 $ 37.81 $ 34.22
Aggregate intrinsic value on exercise $ 31 $ 87 $ 114
Cash received upon exercise 15 36 57
Share-based Payment Arrangement, Exercise of Option, Tax Benefit $ 19 $ 34 $ 39
[1] Market price of underlying Zoetis common stock less exercise price.