Revenue - Revenue by Species (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Revenue from External Customer [Line Items]
Revenues	$ 8,080	$ 7,776	$ 6,675
Cattle
Revenue from External Customer [Line Items]
Revenues	1,440	1,557	1,558
Swine
Revenue from External Customer [Line Items]
Revenues	565	659	621
Poultry
Revenue from External Customer [Line Items]
Revenues	476	507	537
Fish
Revenue from External Customer [Line Items]
Revenues	212	187	148
Other
Revenue from External Customer [Line Items]
Revenues	98	95	76
Livestock
Revenue from External Customer [Line Items]
Revenues	2,791	3,005	2,940
Dogs and Cats
Revenue from External Customer [Line Items]
Revenues	264	263	215
Horses
Revenue from External Customer [Line Items]
Revenues	4,939	4,426	3,437
Companion Animal
Revenue from External Customer [Line Items]
Revenues	5,203	4,689	3,652
Contract Manufacturing and Human Health Diagnostics [Member]
Revenue from External Customer [Line Items]
Revenues	$ 86	$ 82	$ 83