Segment Information - Income Statement (Details) - USD ($) $ in Millions		12 Months Ended
		Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Segment Reporting Information [Line Items]
Revenues		$ 7,776	$ 6,675	$ 6,260
Cost of Sales	[1]	2,303	2,057	1,992
Other (income)/deductions-net		48	17	(57)
Earnings	[2]	2,488	1,996	1,801
Depreciation and Amortization	[2],[3]	448	441	412
Property, plant and equipment, less accumulated depreciation		2,422	2,202
Other business activities
Segment Reporting Information [Line Items]
Earnings		(406)	(372)	(348)
Depreciation and Amortization	[3]	28	27	24
United States
Segment Reporting Information [Line Items]
Revenues		4,042	3,557	3,203
Property, plant and equipment, less accumulated depreciation		1,638	1,486
International
Segment Reporting Information [Line Items]
Property, plant and equipment, less accumulated depreciation		784	716
Operating Segments
Segment Reporting Information [Line Items]
Earnings		4,517	3,786	3,492
Depreciation and Amortization	[3]	128	111	97
Operating Segments | United States Segment
Segment Reporting Information [Line Items]
Revenues		4,042	3,557	3,203
Cost of Sales		788	709	655
Gross Profit		$ 3,254	$ 2,848	$ 2,548
Gross Margin		80.50%	80.10%	79.60%
Operating Expenses		$ 681	$ 602	$ 543
Other (income)/deductions-net		4	(7)	0
Earnings		2,569	2,239	2,005
Depreciation and Amortization	[3]	54	55	44
Operating Segments | International Segment
Segment Reporting Information [Line Items]
Revenues	[4]	3,652	3,035	2,972
Cost of Sales		1,106	971	925
Gross Profit		$ 2,546	$ 2,064	$ 2,047
Gross Margin		69.70%	68.00%	68.90%
Operating Expenses		$ 602	$ 510	$ 560
Other (income)/deductions-net		4	(7)	0
Earnings		1,948	1,547	1,487
Operating Segments | International
Segment Reporting Information [Line Items]
Depreciation and Amortization	[3]	74	56	53
Corporate, Non-Segment
Segment Reporting Information [Line Items]
Earnings		(1,052)	(879)	(755)
Depreciation and Amortization	[3]	115	101	69
Segment Reconciling Items
Segment Reporting Information [Line Items]
Depreciation and Amortization	[3]	0	0	0
Purchase accounting adjustments, earnings		(175)	(198)	(234)
Purchase accounting adjustments, depreciation and amortization	[3]	175	199	219
Acquisition-related costs, earnings		(12)	(18)	(43)
Certain significant items, earnings	[5]	(73)	(43)	(67)
Certain significant items, depreciation and amortization	[3],[5]	0	0	0
Other unallocated, earnings		(311)	(280)	(244)
Other unallocated, deprecation and amortization	[3]	$ 2	$ 3	$ 3

[1] Exclusive of amortization of intangible assets, except as disclosed in Note 3. Significant Accounting Policies—Amortization of Intangible Assets, Depreciation and Certain Long-Lived Assets.

[2] Defined as income before provision for taxes on income.

[3] Certain production facilities are shared. Depreciation and amortization is allocated to the reportable operating segments based on estimates of where the benefits of the related assets are realized.

[4] Revenue denominated in euros was $814 million in 2021, $718 million in 2020 and $742 million in 2019.

[5] For 2021, certain significant items primarily included certain asset impairment charges of $46 million, as well as employee termination costs associated with our international operations and other costs associated with cost-reduction and productivity initiatives of $21 million. For 2020, certain significant items primarily included certain asset impairment charges of $37 million and CEO transition-related costs of $16 million, partially offset by a net gain resulting from a cash payment received pursuant to an agreement related to the 2016 sale of certain U.S. manufacturing sites of $18 million. For 2019, certain significant items primarily includes: (i) a change in estimate related to inventory costing of $69 million, (ii) CEO transition-related costs of $10 million, (iii) consulting fees, product transfer costs, employee termination costs and exit costs related to cost-reduction and productivity initiatives of $7 million, and (iv) income of $20 million resulting from a cash payment received pursuant to an agreement related to the 2016 sale of certain U.S. manufacturing sites.