Acquisitions and Divestitures - Supplemental Pro Forma Financial Information (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2020	Dec. 31, 2019	Dec. 31, 2018
Business Acquisition [Line Items]
Acquisition-related costs	$ 18	$ 43	$ 61
Amortization expense of finite-lived intangible assets	230	237	157
Depreciation expense	211	175	152
Interest expense, net of capitalized interest	231	223	206
Share-based compensation expense	59	67	$ 53
Pro Forma [Member]
Business Acquisition [Line Items]
Acquisition-related costs	82	60
Amortization expense of finite-lived intangible assets	77	130
Depreciation expense	2	3
Adjustment to inventory	18	33
Interest expense, net of capitalized interest	36	57
Abaxis Inc
Business Acquisition [Line Items]
Revenue	5,980	5,542
Net income attributable to Zoetis Inc.	1,402	706
Share-based compensation expense	$ 4	$ 13