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Net loss per share attributable to common stockholders - Summary of outstanding shares of common stock equivalents excluded from computation of diluted net loss per share (Details 1) - shares
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Weighted average shares outstanding:    
Total 2,732,501 1,482,065
Common stock warrants    
Weighted average shares outstanding:    
Total 687,599 359,868
Options    
Weighted average shares outstanding:    
Total 2,044,902 1,122,197