Three Months Ended June 30,

Six Months Ended June 30,

2022

2021

2022

2021

U.S. dollars in thousands

Commercial Operations Segment Adjusted EBITDA

(2,913)

(5,471)

(12,190)

(10,482)

Research And Development Adjusted EBITDA

(3,712)

(11,846)

(6,620)

(21,797)

Financial expenses (income), net

2,552

4,235

6,451

8,946

Share-based compensation to employees and service providers

618

5,274

2,924

6,146

Depreciation

617

465

1,154

957

Amortization and impairment of intangible assets

1,299

1,830

2,900

3,657

Consolidated Comprehensive loss

11,711

29,121

32,239

51,984