X0101 EFFECT 33 LIVE 2017-06-19 0001445546-17-002724 485APOS 0001552740 FIRST TRUST EXCHANGE-TRADED FUND VI 333-182308 S000058144 Developed International Equity Select ETF C000190377 Developed International Equity Select ETF S000058145 Emerging Markets Equity Select ETF C000190378 Emerging Markets Equity Select ETF S000058146 Large Cap US Equity Select ETF C000190379 Large Cap US Equity Select ETF S000058147 Mid Cap US Equity Select ETF C000190380 Mid Cap US Equity Select ETF S000058148 Small Cap US Equity Select ETF C000190381 Small Cap US Equity Select ETF S000058149 US Equity Dividend Select ETF C000190382 US Equity Dividend Select ETF