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        <name>Fifth Third Bancorp</name>
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        <name>HCA Healthcare Inc</name>
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        <name>Jones Lang LaSalle Incorporated</name>
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        <name>The Kroger Co.</name>
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        <name>LKQ Corporation</name>
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        <name>Laboratory Corp of America Holdings</name>
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        <name>Lennar Corporation</name>
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        <name>Lincoln National Corporation</name>
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        <name>Macy's, Inc.</name>
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        <name>Manpowergroup Inc</name>
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        <name>Marathon Petroleum Company</name>
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        <name>Molina Healthcare, Inc.</name>
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        <name>Morgan Stanley</name>
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        <name>The Mosaic Company</name>
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        <name>OneMain Holdings Incorporation</name>
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        <name>Ovintiv Inc</name>
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        <name>Penske Automotive Group, Inc.</name>
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        <name>Principal Financial Group</name>
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        <name>Raymond James Financial Inc.</name>
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        <name>SLM Corporation</name>
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        <name>Selective Insurance Group Inc.</name>
        <lei>549300R3WGJWLE40R258</lei>
        <title>SELECTIVE INSURANCE GROUP</title>
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        <name>Starwood Property Trust, Inc.</name>
        <lei>BUGSFQZERKRBFWIG5267</lei>
        <title>STARWOOD PROPERTY TRUST INC</title>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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      <invstOrSec>
        <name>Stifel Financial Corporation</name>
        <lei>549300E5F07FE5GHJX84</lei>
        <title>STIFEL FINANCIAL CORP</title>
        <cusip>860630102</cusip>
        <identifiers>
          <isin value="US8606301021"/>
          <ticker value="SF"/>
          <other otherDesc="SEDOL" value="2849234"/>
        </identifiers>
        <balance>8290.0000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>583781.80</valUSD>
        <pctVal>2.3180819337</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Synchrony Financial</name>
        <lei>549300RS7EWPM9MA6C78</lei>
        <title>SYNCHRONY FINANCIAL</title>
        <cusip>87165B103</cusip>
        <identifiers>
          <isin value="US87165B1035"/>
          <ticker value="SYF"/>
          <other otherDesc="SEDOL" value="BP96PS6"/>
        </identifiers>
        <balance>8413.0000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>390279.07</valUSD>
        <pctVal>1.5497209082</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Targa Resources Co</name>
        <lei>5493003QENHHS261UR94</lei>
        <title>TARGA RESOURCES CORP</title>
        <cusip>87612G101</cusip>
        <identifiers>
          <isin value="US87612G1013"/>
          <ticker value="TRGP"/>
          <other otherDesc="SEDOL" value="B55PZY3"/>
        </identifiers>
        <balance>7070.0000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>369336.80</valUSD>
        <pctVal>1.4665633008</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Tenet Healthcare Corporation</name>
        <lei>0W9AIBT6U6ADJ2I8HK17</lei>
        <title>TENET HEALTHCARE CORP</title>
        <cusip>88033G407</cusip>
        <identifiers>
          <isin value="US88033G4073"/>
          <ticker value="THC"/>
          <other otherDesc="SEDOL" value="B8DMK08"/>
        </identifiers>
        <balance>4971.0000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>406080.99</valUSD>
        <pctVal>1.6124672036</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>U.S. Bancorp</name>
        <lei>N1GZ7BBF3NP8GI976H15</lei>
        <title>US BANCORP</title>
        <cusip>902973304</cusip>
        <identifiers>
          <isin value="US9029733048"/>
          <ticker value="USB"/>
          <other otherDesc="SEDOL" value="2736035"/>
        </identifiers>
        <balance>3864.0000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>217040.88</valUSD>
        <pctVal>0.8618263584</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Wells Fargo &amp; Company</name>
        <lei>PBLD0EJDB5FWOLXP3B76</lei>
        <title>WELLS FARGO &amp; CO</title>
        <cusip>949746101</cusip>
        <identifiers>
          <isin value="US9497461015"/>
          <ticker value="WFC"/>
          <other otherDesc="SEDOL" value="2649100"/>
        </identifiers>
        <balance>10110.0000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>485077.80</valUSD>
        <pctVal>1.9261478940</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Wesco International, Inc.</name>
        <lei>529900TXOGREY3WNJ434</lei>
        <title>WESCO INTERNATIONAL INC</title>
        <cusip>95082P105</cusip>
        <identifiers>
          <isin value="US95082P1057"/>
          <ticker value="WCC"/>
          <other otherDesc="SEDOL" value="2416973"/>
        </identifiers>
        <balance>5495.0000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>723087.05</valUSD>
        <pctVal>2.8712354978</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Westlake Chemical Corporation</name>
        <lei>GOXNEVUM0LL78B1OS344</lei>
        <title>WESTLAKE CHEMICAL CORP</title>
        <cusip>960413102</cusip>
        <identifiers>
          <isin value="US9604131022"/>
          <ticker value="WLK"/>
          <other otherDesc="SEDOL" value="B01ZP20"/>
        </identifiers>
        <balance>6770.0000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>657570.10</valUSD>
        <pctVal>2.6110806623</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Zions Bancorporation Natl Assn Global Bank</name>
        <lei>8WH0EE09O9V05QJZ3V89</lei>
        <title>ZIONS BANCORP NA</title>
        <cusip>989701107</cusip>
        <identifiers>
          <isin value="US9897011071"/>
          <ticker value="ZION"/>
          <other otherDesc="SEDOL" value="2989828"/>
        </identifiers>
        <balance>6452.0000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>407508.32</valUSD>
        <pctVal>1.6181348484</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <explntrNotes>
      <explntrNote note="Monthly returns presented in Item B.5(a) have been calculated without deducting any applicable sales loads or redemption fees." noteItem="B.5.a"/>
    </explntrNotes>
    <signature>
      <ncom:dateSigned>2022-01-30</ncom:dateSigned>
      <ncom:nameOfApplicant>First Trust Exchange-Traded Fund VI</ncom:nameOfApplicant>
      <ncom:signature>Donald P. Swade</ncom:signature>
      <ncom:signerName>First Trust Exchange-Traded Fund VI </ncom:signerName>
      <ncom:title>Treasurer, Chief Financial Officer and Chief Accounting Officer</ncom:title>
    </signature>
  </formData>
  <documents>XXXX</documents>
</edgarSubmission>
