INCOME TAXES - Income Tax Reconciliation (Details) - USD ($)	12 Months Ended
Dec. 31, 2022	Dec. 31, 2021
Amount
Income tax benefit at statutory rate	$ (9,190,900)	$ (7,726,800)
State income taxes, net of federal tax benefit	(41,000)	(27,900)
Non-deductible expenses	314,900	4,500
Credits	(1,210,000)	(1,176,500)
Foreign rate differential	3,100	2,400
Change in state tax rate	(8,500)	1,764,100
Other	367,500	894,600
Change in valuation allowance	9,764,900	6,265,600
Income tax benefit	$ 0	$ 0
% of Pretax Earnings
Income tax benefit at statutory rate (as a percentage)	21.00%	21.00%
State income taxes, net of federal tax benefit (as a percentage)	0.10%	0.10%
Non-deductible expenses (as a percentage)	(0.70%)	0.00%
Credits (as a percentage)	2.70%	3.20%
Foreign rate differential (as a percentage)	0.00%	0.00%
Change in state tax rate (as a percentage)	0.00%	(4.80%)
Other (as a percentage)	(0.80%)	(2.50%)
Change in valuation allowance (as a percentage)	(22.30%)	(17.00%)
Income tax benefit (as a percentage)	0.00%	0.00%

Effective Income Tax Rate Reconciliation, Change in Enacted Tax Rate, State and Local, Amount

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Percentage of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.

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