INCOME TAXES - Deferred Tax Assets and Liabilities (Details) - USD ($)	Dec. 31, 2022	Dec. 31, 2021
Income Tax Disclosure [Abstract]
Domestic tax loss and contribution carryforwards	$ 21,419,800	$ 18,656,500
Foreign tax loss carryforwards	4,531,900	5,134,700
Tax credits	3,718,100	2,534,600
Share-based compensation	3,908,000	3,647,100
Intangible assets	2,957,100	3,096,800
Accrued expenses	114,300	371,200
Section 174 - capitalized research and development	5,940,400	0
Research and development expenses	0	20,500
Other	19,200	5,900
Valuation allowance	(42,608,800)	(33,467,300)
Total deferred tax assets, noncurrent	$ 0	$ 0