Stockholders' Equity (Tables)

6 Months Ended

Jun. 30, 2023

Share-Based Payment Arrangement [Abstract]

Summary of option activity

The following summarizes all option activity under the 2007 Plan, 2014 Plan and Inducement Plan:

				Weighted		Weighted average
				average		remaining
	Option			exercise		contractual
	Shares			price		term (year)
Balance at December 31, 2022		89,678		$	42.78		7.11
Forfeited		(2,619	)		139.79
Balance at June 30, 2023		87,059		$	39.86		6.78

Summary of RSUs activity

Activity related to RSUs is set forth below:

				Weighted average
	Number			grant date
	of shares			fair value
Balance at December 31, 2022		708,806		$	43.86
Granted		574,200			1.71
Vested		(147,924	)		24.91
Forfeited		(61,626	)		12.05
Balance at June 30, 2023		1,073,456		$	25.75