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Licensing, Acquisitions and Other Arrangements (Details) - USD ($)
$ in Millions
3 Months Ended 9 Months Ended
Sep. 30, 2023
Sep. 30, 2022
Jun. 30, 2022
Sep. 30, 2023
Sep. 30, 2022
Feb. 28, 2022
Collaborative and license agreements            
Cash outflows related to acquisitions and investments       $ (670) $ (494)  
Acquired IPR&D and milestones $ 66 $ 40   496 454  
Gain on divestitures         172  
Collaborative arrangement            
Collaborative and license agreements            
Research and development milestone expenses 22 0   100 62  
Syndesi | Collaborative arrangement            
Collaborative and license agreements            
Acquired IPR&D and milestones   130        
Syndesi | Collaborative arrangement | Maximum            
Collaborative and license agreements            
Potential payments under agreement certain milestones           $ 870
Juvise Pharmaceuticals | Other operating income (expense)            
Collaborative and license agreements            
Gain on divestitures     $ 172      
Juvise Pharmaceuticals | Collaborative arrangement            
Collaborative and license agreements            
Proceeds from sale of assets     $ 215      
Other Collaboration Arrangements | Collaborative arrangement            
Collaborative and license agreements            
Acquired IPR&D and milestones $ 44 $ 40   $ 396 $ 262