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Income Taxes - Effective Tax Rate Reconciliation (Details) - USD ($)
$ in Billions
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Effective Income Tax Rate Reconciliation, Percent [Abstract]      
Statutory tax rate 21.00% 21.00% 21.00%
Effect of foreign operations (5.40%) 2.40% (8.40%)
U.S. tax credits (2.80%) (10.60%) (3.30%)
Impacts related to U.S. tax reform 0.00% (1.10%) (1.60%)
Non-deductible expenses 0.30% 7.20% 1.00%
Tax law changes and related restructuring (2.00%) (48.50%) 3.10%
Tax audit settlements (0.40%) (5.10%) (4.70%)
All other, net 0.40% (1.30%) (0.60%)
Effective tax rate 11.10% (36.00%) 6.50%
Amount of net tax benefit related to changes in tax laws and related restructuring, including certain intra-group transfers of intellectual property and deferred tax remeasurement   $ 1.7