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Financial Instruments and Fair Value Measures - Fair Value Measures (Details) - USD ($) $ in Millions	3 Months Ended		12 Months Ended
	Sep. 30, 2019	Jun. 30, 2019	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Assets
Foreign currency contracts			$ 267	$ 189
Liabilities
Foreign currency contracts			37	166
Change in fair value recognized in net earnings			(2,679)	(5,753)	$ (3,091)
Stemcentrx Inc.
Liabilities
Change in fair value recognized in net earnings	$ 91
Skyrizi
Liabilities
Change in fair value recognized in net earnings		$ (2,300)	(2,700)	(5,700)
Recurring
Assets
Cash and equivalents			9,746	8,449
Debt securities			46	50
Equity securities			121	159
Interest rate swap contracts			26	138
Total assets			10,225	8,859
Liabilities
Interest rate swap contracts			22	34
Contingent consideration			14,887	12,997
Total liabilities			14,924	13,163
Recurring \| Money market funds
Assets
Money market funds and time deposits			45	12
Recurring \| Foreign currency contracts
Assets
Foreign currency contracts			241	51
Liabilities
Foreign currency contracts			15	132
Recurring \| Quoted prices in active markets for identical assets (Level 1)
Assets
Cash and equivalents			4,451	2,758
Debt securities			0	0
Equity securities			100	149
Interest rate swap contracts			0	0
Total assets			4,551	2,907
Liabilities
Interest rate swap contracts			0	0
Contingent consideration			0	0
Total liabilities			0	0
Recurring \| Quoted prices in active markets for identical assets (Level 1) \| Money market funds
Assets
Money market funds and time deposits			0	0
Recurring \| Quoted prices in active markets for identical assets (Level 1) \| Foreign currency contracts
Assets
Foreign currency contracts			0	0
Liabilities
Foreign currency contracts			0	0
Recurring \| Significant other observable inputs (Level 2)
Assets
Cash and equivalents			5,295	5,691
Debt securities			46	50
Equity securities			21	10
Interest rate swap contracts			26	138
Total assets			5,674	5,952
Liabilities
Interest rate swap contracts			22	34
Contingent consideration			0	0
Total liabilities			37	166
Recurring \| Significant other observable inputs (Level 2) \| Money market funds
Assets
Money market funds and time deposits			45	12
Recurring \| Significant other observable inputs (Level 2) \| Foreign currency contracts
Assets
Foreign currency contracts			241	51
Liabilities
Foreign currency contracts			15	132
Recurring \| Significant unobservable inputs (Level 3)
Assets
Cash and equivalents			0	0
Debt securities			0	0
Equity securities			0	0
Interest rate swap contracts			0	0
Total assets			0	0
Liabilities
Interest rate swap contracts			0	0
Contingent consideration			14,887	12,997
Total liabilities			14,887	12,997
Recurring \| Significant unobservable inputs (Level 3) \| Money market funds
Assets
Money market funds and time deposits			0	0
Recurring \| Significant unobservable inputs (Level 3) \| Foreign currency contracts
Assets
Foreign currency contracts			0	0
Liabilities
Foreign currency contracts			$ 0	$ 0