The aggregate expense charged against earnings to allocate the cost of intangible assets (nonphysical assets not used in production) in a systematic and rational manner to the periods expected to benefit from such assets. As a noncash expense, this element is added back to net income when calculating cash provided by or used in operations using the indirect method.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Amount of increase (decrease) in carrying value of assets, excluding financial assets and goodwill, lacking physical substance with a finite life.

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Goodwill and Intangible Assets - Definite-Lived Intangible Assets (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Definite-lived intangible assets
Reclass to developed product rights	$ 1,000
Reclassification from indefinite-lived intangible assets	(1,000)
Amortization of intangible assets	7,718	$ 5,805	$ 1,553
Anticipated annual amortization expense
2022	7,200
2023	7,500
2024	8,000
2025	8,400
2026	$ 7,900
Minimum
Definite-lived intangible assets
Amortization period	1 year
Maximum
Definite-lived intangible assets
Amortization period	16 years
Weighted Average \| Developed product rights
Definite-lived intangible assets
Amortization period	12 years
Weighted Average \| License agreements
Definite-lived intangible assets
Amortization period	11 years