Goodwill and Intangible Assets - Summary of Intangible Assets (Details) - USD ($) $ in Millions	Dec. 31, 2021	Dec. 31, 2020
Definite-lived intangible assets
Gross carrying amount	$ 97,432	$ 95,535
Accumulated amortization	(22,151)	(14,536)
Net carrying amount	75,281	80,999
Indefinite-lived research and development	670	1,877
Total intangible assets gross carrying amount	98,102	97,412
Total intangible assets, net	75,951	82,876
Developed product rights
Definite-lived intangible assets
Gross carrying amount	88,945	87,707
Accumulated amortization	(18,463)	(11,620)
Net carrying amount	70,482	76,087
License agreements
Definite-lived intangible assets
Gross carrying amount	8,487	7,828
Accumulated amortization	(3,688)	(2,916)
Net carrying amount	$ 4,799	$ 4,912

Accumulated amount of amortization of assets, excluding financial assets and goodwill, lacking physical substance with a finite life.

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Amount before amortization of assets, excluding financial assets and goodwill, lacking physical substance with a finite life.

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Sum of the carrying amounts of all intangible assets, excluding goodwill, as of the balance sheet date, net of accumulated amortization and impairment charges.

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