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Goodwill and Intangible Assets - Goodwill (Details) - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Changes in the carrying amount of goodwill    
Balance at the beginning of the period $ 33,124,000,000 $ 15,604,000,000
Additions 177,000,000 [1] 17,008,000,000 [2]
Goodwill measurement period adjustments [3] (564,000,000)  
Foreign currency translation adjustments and other (358,000,000) 512,000,000
Balance at the end of the period 32,379,000,000 $ 33,124,000,000
Accumulated goodwill impairment losses    
Accumulated goodwill impairment losses $ 0  
[1] Goodwill additions related to the acquisition of Soliton in the fourth quarter of 2021 (see Note 5).
[2] Goodwill additions related to the acquisition of Allergan in the second quarter of 2020 and the acquisition of Luminera in the fourth quarter of 2020 (see Note 5).
[3] Measurement period adjustments recorded in 2021 related to the acquisition of Allergan (see Note 5).