Licensing, Acquisitions, and Other Arrangements - Acquisition of Soliton, Inc. (Details) - USD ($) $ in Millions	1 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Business Acquisition
Goodwill	$ 32,379	$ 33,124	$ 15,604
Solition, Inc.
Business Acquisition
Total consideration	535
Intangible assets - Developed product rights	407
Deferred tax liabilities	63
Goodwill	$ 177