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Licensing, Acquisitions, and Other Arrangements - Other Licensing & Acquisitions Activity (Details) - USD ($)
$ in Millions
1 Months Ended 3 Months Ended 12 Months Ended
Oct. 31, 2019
Jun. 30, 2018
Dec. 31, 2019
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Collaborative Arrangements and Non-collaborative Arrangement Transactions            
Cash outflows related to other acquisitions and investments       $ 1,135 $ 736 $ 308
Acquired in-process research and development       385 424 327
Other operating expense (income)       890 (500) 0
Collaborative arrangement            
Collaborative Arrangements and Non-collaborative Arrangement Transactions            
Additional contribution to collaboration   $ 500        
Reata Pharmaceuticals Inc            
Collaborative Arrangements and Non-collaborative Arrangement Transactions            
Other operating expense (income)     $ 330      
Calico Life Sciences LLC | Collaborative arrangement            
Collaborative Arrangements and Non-collaborative Arrangement Transactions            
Additional contribution to collaboration by partner   $ 500        
Term by which the agreement was extended   3 years        
Other operating expense (income)         (500)  
Alector, Inc. | Collaborative arrangement            
Collaborative Arrangements and Non-collaborative Arrangement Transactions            
Acquired in-process research and development           205
Potential additional milestone payments     986 986    
Other individually insignificant arrangements | Collaborative arrangement            
Collaborative Arrangements and Non-collaborative Arrangement Transactions            
Acquired in-process research and development       385 $ 424 $ 122
Other individually insignificant arrangements | Maximum            
Collaborative Arrangements and Non-collaborative Arrangement Transactions            
Potential additional milestone payments     $ 5,800 $ 5,800    
Other operating income | Reata Pharmaceuticals Inc            
Collaborative Arrangements and Non-collaborative Arrangement Transactions            
Consideration receivable for reacquired rights $ 330