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Goodwill and Intangible Assets (Tables)
12 Months Ended
Dec. 31, 2019
Goodwill and Intangible Assets Disclosure [Abstract]  
Summary of changes in the carrying amount of goodwill
The following table summarizes the changes in the carrying amount of goodwill:
(in millions)
 
Balance as of December 31, 2017
$
15,785

Foreign currency translation
(122
)
Balance as of December 31, 2018
15,663

Foreign currency translation
(59
)
Balance as of December 31, 2019
$
15,604


Schedule of definite-lived intangible assets
The following table summarizes intangible assets:
 
2019
 
2018
as of December 31 (in millions)
Gross
 carrying
 amount
 
Accumulated
 amortization
 
Net
 carrying
 amount
 
Gross
 carrying
 amount
 
Accumulated
 amortization
 
Net
 carrying
 amount
Definite-lived intangible assets
 
 
 
 
 
 
 
 
 
 
 
Developed product rights
$
19,547

 
$
(6,405
)
 
$
13,142

 
$
15,872

 
$
(5,614
)
 
$
10,258

License agreements
7,798

 
(2,291
)
 
5,507

 
7,865

 
(1,810
)
 
6,055

Total definite-lived intangible assets
27,345

 
(8,696
)
 
18,649

 
23,737

 
(7,424
)
 
16,313

Indefinite-lived research and development

 

 

 
4,920

 

 
4,920

Total intangible assets, net
$
27,345

 
$
(8,696
)
 
$
18,649

 
$
28,657

 
$
(7,424
)
 
$
21,233


Schedule of indefinite-lived intangible assets
The following table summarizes intangible assets:
 
2019
 
2018
as of December 31 (in millions)
Gross
 carrying
 amount
 
Accumulated
 amortization
 
Net
 carrying
 amount
 
Gross
 carrying
 amount
 
Accumulated
 amortization
 
Net
 carrying
 amount
Definite-lived intangible assets
 
 
 
 
 
 
 
 
 
 
 
Developed product rights
$
19,547

 
$
(6,405
)
 
$
13,142

 
$
15,872

 
$
(5,614
)
 
$
10,258

License agreements
7,798

 
(2,291
)
 
5,507

 
7,865

 
(1,810
)
 
6,055

Total definite-lived intangible assets
27,345

 
(8,696
)
 
18,649

 
23,737

 
(7,424
)
 
16,313

Indefinite-lived research and development

 

 

 
4,920

 

 
4,920

Total intangible assets, net
$
27,345

 
$
(8,696
)
 
$
18,649

 
$
28,657

 
$
(7,424
)
 
$
21,233


Schedule of anticipated annual amortization expense The anticipated annual amortization expense for definite-lived intangible assets recorded as of December 31, 2019 is as follows:
(in billions)
2020
 
2021
 
2022
 
2023
 
2024
Anticipated annual amortization expense
$
1.8

 
$
2.0

 
$
2.3

 
$
2.4

 
$
2.5