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Quarterly Financial Data (unaudited) (Details) - USD ($)
$ / shares in Units, shares in Millions, $ in Millions
1 Months Ended 3 Months Ended 12 Months Ended
May. 15, 2015
May. 15, 2014
Jan. 04, 2013
Oct. 31, 2014
Dec. 31, 2015
Sep. 30, 2015
Jun. 30, 2015
Mar. 31, 2015
Dec. 31, 2014
Sep. 30, 2014
Jun. 30, 2014
Mar. 31, 2014
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Net revenues         $ 6,400 $ 5,944 $ 5,475 $ 5,040 $ 5,452 $ 5,019 $ 4,926 $ 4,563 $ 22,859 $ 19,960 $ 18,790
Gross margin         4,925 4,777 4,559 4,098 4,333 3,925 3,813 3,463      
Net earnings         $ 1,517 $ 1,239 $ 1,366 $ 1,022 $ (810) $ 506 $ 1,098 $ 980 $ 5,144 $ 1,774 $ 4,128
Basic earnings per share (in dollars per share)         $ 0.93 $ 0.75 $ 0.84 $ 0.64 $ (0.51) $ 0.32 $ 0.69 $ 0.61 $ 3.15 $ 1.11 $ 2.58
Diluted earnings per share (in dollars per share)         0.92 0.74 0.83 0.63 (0.51) 0.31 0.68 0.61 3.13 1.10 2.56
Cash dividends declared per common share (in dollars per share)     $ 0.40   $ 0.57 $ 0.51 $ 0.51 $ 0.51 $ 0.49 $ 0.42 $ 0.42 $ 0.42 $ 2.10 $ 1.75 $ 2.00 [1]
Royalty revenue                           $ 81  
Milestone revenue                         $ 40    
Increase litigation reserves         $ 101                    
Cash Dividends                              
Anti-dilutive securities excluded from the computation of earnings per common share (in shares)                 36            
C2N Diagnostics                              
Initial upfront payment               $ 100              
HCV                              
Payments to collaborators                     $ 40        
Rare Pediatric Disease Priority Review Voucher From United Therapeutics Corporation                              
Research and development expense           $ 350                  
Calico Life Sciences LLC                              
Initial upfront payment                         500 250  
Research and development expense                 $ 500            
Payments to collaborators                   $ 250          
Infinity Pharmaceuticals Inc                              
Payments to collaborators           83       173          
Dividend Paid Quarter One                              
Cash Dividends                              
Date declared               Feb. 19, 2015       Feb. 20, 2014      
Dividends paid (in dollars per share) $ 0.51 $ 0.42                          
Pharmacyclics Inc                              
Net revenues                         $ 774    
Acquisition-related and financing-related costs         $ 68 $ 85 $ 215 $ 41              
Shire plc                              
Foreign exchange loss associated with forward contracts               $ (170)           (490)  
Acquisition-related and financing-related costs                           $ 1,800  
Break fee       $ 1,600         $ 1,600            
Shire plc | Calico Life Sciences LLC                              
Payments to collaborators                   $ 172          
[1] On January 4, 2013, a cash dividend of $0.40 per share of common stock was declared from pre-separation earnings and was recorded as a reduction of additional paid-in capital.