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Collaboration with Janssen Biotech, Inc. (Details) - Collaborative arrangement - USD ($)
$ in Millions
12 Months Ended 24 Months Ended
May. 26, 2015
Dec. 31, 2015
Dec. 31, 2015
Collaborative and license agreements      
Share of collaboration development costs responsible by the entity (as a percent) 40.00%    
Outside of United States      
Collaborative and license agreements      
Share of pretax profits under collaboration   $ 95  
Cost sharing expenses under collaboration   159  
Janssen Biotech, Inc      
Collaborative and license agreements      
Share of collaboration development costs responsible by Janssen (as a percent) 60.00%    
Janssen Biotech, Inc | United States      
Collaborative and license agreements      
Expense recorded for profit sharing before taxes to other party     $ 306
Janssen Biotech, Inc | Accounts and other receivables, net      
Collaborative and license agreements      
Amounts receivable   45 45
Janssen Biotech, Inc | Accounts payable and accrued liabilities      
Collaborative and license agreements      
Amounts payable   $ 134 $ 134
Pharmacyclics Inc | Janssen Biotech, Inc      
Collaborative and license agreements      
Milestone payments $ 200