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Licensing, Acquisitions and Other Arrangements (Details 3) - USD ($)
$ / shares in Units, $ in Millions
1 Months Ended 3 Months Ended 12 Months Ended
Oct. 31, 2014
Dec. 31, 2015
Sep. 30, 2015
Jun. 30, 2015
Mar. 31, 2015
Dec. 31, 2014
Jun. 30, 2013
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Acquisitions                    
Cash outflows related to other acquisitions and investments               $ 964 $ 622 $ 405
Cash outflows related to acquisitions and investments               11,488    
Acquired in-process research and development               150 352 338
Pro forma combined results of operations                    
Net revenues               23,215 20,690  
Net earnings               $ 5,345 $ 812  
Basic earnings per share               $ 3.18 $ 0.47  
Diluted earnings per share               $ 3.16 $ 0.47  
C2N Diagnostics                    
Acquisitions                    
Initial upfront payment         $ 100          
Additional payment   $ 685           $ 685    
Calico Life Sciences LLC                    
Acquisitions                    
Initial upfront payment               $ 500 $ 250  
Research and development expense           $ 500        
Research and early development term               5 years    
Advance collaboration projects term               10 years    
Rare Pediatric Disease Priority Review Voucher From United Therapeutics Corporation                    
Acquisitions                    
Research and development expense     $ 350              
Research And Development Expense | Alvine Pharmaceuticals, Inc.                    
Acquisitions                    
Initial upfront payment             $ 70      
Research And Development Expense | Infinity Pharmaceuticals, Inc.                    
Acquisitions                    
Additional payment   400           $ 400    
Research and development expense               130    
Research And Development Expense | Rare Pediatric Disease Priority Review Voucher From United Therapeutics Corporation                    
Acquisitions                    
Research and development expense               350    
IPR&D                    
Acquisitions                    
Research and development expense               150 352 $ 338
IPR&D | C2N Diagnostics                    
Acquisitions                    
Initial upfront payment               $ 100    
IPR&D | Infinity Pharmaceuticals, Inc.                    
Acquisitions                    
Initial upfront payment                 275  
Other Expense | Calico Life Sciences LLC                    
Acquisitions                    
Payments relating to collaboration                 750  
Pharmacyclics Inc                    
Termination of Combination with Shire                    
Acquisition-related and financing-related costs   $ 68 $ 85 $ 215 41          
Shire plc                    
Termination of Combination with Shire                    
Acquisition-related and financing-related costs                 1,800  
Break fee $ 1,600         $ 1,600        
Foreign exchange loss associated with forward contracts         170       490  
Shire plc | Selling General And Administrative Expenses                    
Termination of Combination with Shire                    
Acquisition-related and financing-related costs                 1,700  
Shire plc | Interest Expense                    
Termination of Combination with Shire                    
Acquisition-related and financing-related costs                 141  
Foreign currency forward exchange contracts | Shire plc                    
Termination of Combination with Shire                    
Foreign exchange loss associated with forward contracts         $ 170       $ 666