Income Taxes - Additional Information (Details) - USD ($)	12 Months Ended
	Nov. 30, 2022	Nov. 30, 2021	Nov. 30, 2020
Income Tax Examination [Line Items]
Current income tax expense (benefit)	$ 0	$ 100,000
Increase in valuation allowance	54,800,000	36,100,000
Net operating loss unutilized amount	400,000
Unrecognized tax benefits	10,261,000	6,331,000	$ 5,361,000
Unrecognized tax benefits that would impact effective tax rate	0
Interest and penalties accrued	0
Decrease in R&D credit carryforward	$ 1,300,000
CARES act of 2020, net operating loss carryback refund claim		$ 19,600,000
CARES act of 2020, net operating loss carryback period	5 years
Federal
Income Tax Examination [Line Items]
NOL carryforwards	$ 276,300,000
Net operating losses carry forward period	20 years
NOL carryforwards, expiration year	2029
NOL carryforwards, indefinitely	$ 272,900,000
Period open for examination	3 years
Federal | Research
Income Tax Examination [Line Items]
Tax credit carryforwards	$ 22,100,000
Credit carryforwards, expiration year	2032
State Authorities
Income Tax Examination [Line Items]
NOL carryforwards	$ 299,600,000
NOL carryforwards, expiration year	2029
Period open for examination	4 years
State Authorities | Research
Income Tax Examination [Line Items]
Tax credit carryforwards	$ 15,200,000
Credit carryforwards, expiration period	indefinitely