CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) $ in Thousands	12 Months Ended
	Nov. 30, 2022	Nov. 30, 2021
Income Statement [Abstract]
Collaboration revenue	$ 38,627	$ 29,750
Operating expenses:
Research and development	184,497	116,434
General and administrative	37,997	31,202
Total operating expenses	222,494	147,636
Loss from operations	(183,867)	(117,886)
Interest and other income, net	3,507	823
Loss before income taxes	(180,360)	(117,063)
Provision for income taxes	0	131
Net loss	$ (180,360)	$ (117,194)
Net loss per share, basic (in USD per share)	$ (3.71)	$ (2.73)
Net loss per share, diluted (in USD per share)	$ (3.71)	$ (2.73)
Weighted-average number of shares outstanding, diluted (in shares)	48,607,990	42,895,383
Weighted average number of shares outstanding, basic (in shares)	48,607,990	42,895,383