X0306 4 2022-08-09 0 0001549595 Nurix Therapeutics, Inc. NRIX 0001817160 Hansen Gwenn C/O NURIX THERAPEUTICS, INC. 1700 OWENS STREET, SUITE 205 SAN FRANCISCO CA 94158 0 1 0 0 Chief Scientific Officer Employee Stock Option (right to buy) 18.50 2022-08-09 4 A 0 60298 0.00 A 2032-08-08 Common Stock 60298 60298 D The stock option vests as to 1/48 of the total shares monthly beginning September 9, 2022 until the option is fully vested on August 9, 2026, subject to the Reporting Person's provision of service to the Issuer on each vesting date. /s/ Christine Ring, as Attorney-in-Fact for Gwenn Hansen 2022-08-10