X0306 4 2021-10-01 0 0001549595 Nurix Therapeutics, Inc. NRIX 0001305361 Reinsdorf Judith A C/O NURIX THERAPEUTICS, INC. 1700 OWENS STREET, SUITE 205 SAN FRANCISCO CA 94158 1 0 0 0 Director Stock Option (right to buy) 31.24 2021-10-01 4 A 0 35000 0.00 A 2031-09-30 Common Stock 35000 35000 D The stock option vests as to 1/36 of the total shares monthly beginning November 1, 2021 until the option is fully vested on October 1, 2024, subject to the Reporting Person's provision of service to the Issuer on each vesting date. /s/ Christine Ring, as Attorney-in-Fact for Judith A. Reinsdorf 2021-10-04