X0306 4 2021-05-06 0 0001549595 Nurix Therapeutics, Inc. NRIX 0001734422 Lacey David L. C/O NURIX THERAPEUTICS, INC. 1700 OWENS STREET, SUITE 205 SAN FRANCISCO CA 94158 1 0 0 0 Director Stock Option (right to buy) 27.38 2021-05-06 4 A 0 17500 0.00 A 2031-05-05 Common Stock 17500 17500 D The stock option vests as to 100% of the award on the earlier of (a) the date of the next annual meeting of the Issuer's stockholders and (b) May 6, 2022, in each case, subject to the Reporting Person's provision of service to the Issuer on such vesting date. /s/ Christine Ring, as Attorney-in-Fact for David L. Lacey 2021-05-24