X0306 4 2021-05-07 1 0001549595 Nurix Therapeutics, Inc. NRIX 0001347769 COLUMN GROUP L P 1700 OWENS STREET SUITE 500 SAN FRANCISCO CA 94158 0 0 1 0 0001606074 Svennilson Peter 1700 OWENS STREET SUITE 500 SAN FRANCISCO CA 94158 0 0 1 0 Common Stock 2021-05-05 4 J 0 2000000 0.00 D 1394333 D Common Stock 2021-05-05 4 J 0 438338 0.00 A 438338 I See Footnote Common Stock 2021-05-05 4 J 0 10307 0.00 A 10307 I See Footnote Common Stock 2021-05-05 4 J 0 10307 0.00 A 10307 I See Footnote Common Stock 2021-05-05 4 J 0 10307 0.00 A 10307 I See Footnote Common Stock 2021-05-05 4 J 0 438338 0.00 D 0 I See Footnote Common Stock 2021-05-05 4 J 0 105874 0.00 A 116181 I See Footnote Common Stock 2021-05-05 4 J 0 111247 0.00 A 121554 I See Footnote Common Stock 2021-05-05 4 J 0 30347 0.00 A 40654 I See Footnote Common Stock 2021-05-05 4 J 0 1000000 0.00 D 989000 I See Footnote Common Stock 2021-05-05 4 J 0 49689 0.00 A 49689 I See Footnote Common Stock 2021-05-05 4 J 0 49689 0.00 D 0 I See Footnote Common Stock 2021-05-05 4 J 0 17829 0.00 A 134010 I See Footnote Common Stock 2021-05-05 4 J 0 17829 0.00 A 139383 I See Footnote Common Stock 2021-05-05 4 J 0 7752 0.00 A 48406 I See Footnote Common Stock 686274 I See Footnote Common Stock 686274 I See Footnote Represents a pro-rata distribution, and not a purchase or sale, without additional consideration by The Column Group, LP ("TCG LP") to its general and limited partners. The securities are directly held by TCG LP, and indirectly held by The Column Group GP, LP ("TCG GP"), the general partner of TCG LP. The managing partners of TCG GP are David Goeddel and Peter Svennilson (the "Managing Partners"). The Managing Partners may be deemed to have voting and investment power with respect to such shares. Each individual Managing Partner disclaims beneficial ownership of these shares, except to the extent of his pecuniary interest in such shares. Represents a change in the form of ownership of TCG GP by virtue of the receipt of shares as a result of the pro-rata in-kind distribution of common stock of the Issuer for no consideration by TCG LP. The securities are directly held by TCG GP. The Managing Partners may be deemed to share voting and investment power with respect to such shares. Each of the Managing Partners disclaim beneficial ownership of these shares, except to the extent of their respective pecuniary interest in such shares. Represents a change in the form of ownership of Peter Svennilson by virtue of the receipt of shares as a result of the pro-rata in-kind distribution of common stock of the Issuer for no consideration by TCG LP. The securities are directly held by Peter Svennilson Represents a change in the form of ownership of David Goeddel by virtue of the receipt of shares as a result of the pro-rata in-kind distribution of common stock of the Issuer for no consideration by TCG LP. The securities are directly held by David Goeddel. Represents a change in the form of ownership of Tim Kutzkey by virtue of the receipt of shares as a result of the pro-rata in-kind distribution of common stock of the Issuer for no consideration by TCG LP. The securities are directly held by Tim Kutzkey. Represents a pro-rata distribution, and not a purchase or sale, without additional consideration by TCG GP to its general and limited partners. Represents a change in the form of ownership of Peter Svennilson by virtue of the receipt of shares as a result of the pro-rata in-kind distribution of common stock of the Issuer for no consideration by TCG GP. Represents a change in the form of ownership of David Goeddel by virtue of the receipt of shares as a result of the pro-rata in-kind distribution of common stock of the Issuer for no consideration by TCG GP. Represents a change in the form of ownership of Tim Kutzkey by virtue of the receipt of shares as a result of the pro-rata in-kind distribution of common stock of the Issuer for no consideration by TCG GP. Represents a pro-rata distribution, and not a purchase or sale, without additional consideration by The Column Group II, LP ("TCG II LP") to its general and limited partners. The securities are directly held by TCG II LP, and indirectly held by The Column Group II GP, LP ("TCG II GP"), the general partner of TCG II LP. The managing partners of TCG II GP are the Managing Partners. The Managing Partners may be deemed to have voting and investment power with respect to such shares. Each individual Managing Partner disclaims beneficial ownership of these shares, except to the extent of his pecuniary interest in such shares. Represents a change in the form of ownership of TCG II GP by virtue of the receipt of shares as a result of the pro-rata in-kind distribution of common stock of the Issuer for no consideration by TCG II LP. The securities are directly held by TCG II GP. The Managing Partners may be deemed to share voting and investment power with respect to such shares. Each of the Managing Partners disclaim beneficial ownership of these shares, except to the extent of their respective pecuniary interest in such shares. Represents a pro-rata distribution, and not a purchase or sale, without additional consideration by TCG II GP to its general and limited partners. Represents a change in the form of ownership of Peter Svennilson by virtue of the receipt of shares as a result of the pro-rata in-kind distribution of common stock of the Issuer for no consideration by TCG II GP. Represents a change in the form of ownership of David Goeddel by virtue of the receipt of shares as a result of the pro-rata in-kind distribution of common stock of the Issuer for no consideration by TCG II GP. Represents a change in the form of ownership of Tim Kutzkey by virtue of the receipt of shares as a result of the pro-rata in-kind distribution of common stock of the Issuer for no consideration by TCG II GP. The securities are directly held by Ponoi Capital, LP ("Ponoi LP"), and indirectly held by Ponoi Management, LLC ("Ponoi LLC"), the general partner of Ponoi LP. The managing partners of Ponoi LLC are David Goeddel, Peter Svennilson and Tim Kutzkey. The managing partners of Ponoi LLC may be deemed to have voting and investment power with respect to such shares. Each individual managing partner disclaims beneficial ownership of these shares, except to the extent of his pecuniary interest in such shares. The securities are directly held by Ponoi Capital II, LP ("Ponoi II LP"), and indirectly held by Ponoi II Management, LLC ("Ponoi II LLC"), the general partner of Ponoi II LP. The managing partners of Ponoi II LLC are David Goeddel, Peter Svennilson and Tim Kutzkey. The managing partners of Ponoi II LLC may be deemed to have voting and investment power with respect to such shares. Each individual managing partner disclaims beneficial ownership of these shares, except to the extent of his pecuniary interest in such shares. Due to SEC restrictions on the number of reporting owners, this is Form 2 of 2. /s/ James Evangelista, as Attorney-in-fact for Peter Svennilson 2021-05-07 /s/ James Evangelista, as Attorney-in-fact for The Column Group, LP 2021-05-07