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Stock Compensation (Tables)
 6 Months Ended
Jun. 30, 2022
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Schedule of Stock Based Compensation Expense Company’s Condensed Consolidated Statement of Operations for the three and six months ended June 30, 2022:
Three Months Ended June 30,Six Months Ended June 30,
2022202120222021
Research and development$125 $45 $227 $122 
General and administrative242 366 468 409 
Total$367 $411 $695 $531 
Summary of Information About Stock Options Outstanding
The following table summarizes information about stock options outstanding at June 30, 2022:

SharesWeighted Average Remaining Contractual Life (In Years)Weighted Average Exercise PriceAggregate Intrinsic Value
Options outstanding1,649,4619.03$8.72$1
Vested and expected to vest1,649,4619.03$8.72$1
Exercisable417,0337.84$15.91$—
Summary of Stock Options The following shows the stock option activities for the six months ended June 30, 2022 and 2021:
Total Options OutstandingWeighted-Average Exercise Price
Balance—December 31, 2021790,637 $32.82 
Granted893,527 3.36 
Exercised— — 
Cancelled and forfeited(34,703)428.76 
Balance—June 30, 20221,649,461 8.72 
Balance—December 31, 2020452,165 $5.35 
Assumed in reverse recapitalization178,732 178.64 
Granted186,482 20.99 
Exercised(10,654)4.60 
Cancelled and forfeited(6,316)18.36 
Balance—June 30, 2021800,409 47.70 
Share-based Payment Arrangement, Employee  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Summary of Grant Date Fair Value The fair value of stock options was estimated using the following assumptions for the six months ended June 30, 2022 and 2021:
20222021
Expected term (in years)
5.5 - 6.1
6.0 - 6.1
Expected volatility
110% - 112%
67%
Risk-free interest rate
1.5% - 3.4%
1.0% - 1.1%
Dividends
—%
—%