X0306 4 2017-01-27 0 0001590560 uniQure N.V. QURE 0001542768 Cantor Maria E C/O UNIQURE N.V. MEIBERGDREFF 61 AMSTERDAM P7 1005 BA NETHERLANDS 0 1 0 1 SVP, Investor Relations SVP, Investor Communications Stock Option (Right to Buy) 5.37 2017-01-27 4 A 0 43250 0 A 2027-01-27 Ordinary Shares 43250 43250 D Preformance Share Unit 0 2017-01-27 4 A 0 43250 0 A Ordinary Shares 43250 43250 D The Stock Option vests 25% on January 27, 2018 and 6.25% quarterly thereafter until fully vested. Performance Shares Units of a maximum of 43,250 shares of the Company's Ordinary Shares were granted on January 27, 2017. The Board of Directors shall determine how many Performance Share Units are to be granted in conjunction with a review of certain performance goals associated with the grant. Any such Performance Share Units granted by the Board of Directors shall vest 100% on January 27, 2020. Expiration date is not applicable. See Exhibit 24 - Power of Attorney Lauren M. Watson, Attorney-in-Fact 2017-01-31