The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

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COLUMN 1COLUMN 2COLUMN 3COLUMN 4COLUMN 5COLUMN 6COLUMN 7COLUMN 8
VALUESHRS ORSH/PUT/INVESTMENTOTHERVOTING AUTHORITY
NAME OF ISSUERTITLE OF CLASSCUSIP(x$1000)PRN AMTPRNCALLDISCRETIONMANAGERSOLESHAREDNONE
AQUABOUNTY TECHNOLOGIES INCCOM NEW03842K2007,454930,530SH SOLE 930,53000
AQUABOUNTY TECHNOLOGIES INCCOM NEW03842K20041,3505,162,277SH DFND 5,162,27700
ENERGY TRANSFER EQUITY L PCOM UT LTD PTN29273V10015,224847,650SH SOLE 847,65000
ENERGY TRANSFER PARTNERS LPUNIT LTD PRT INT29278N1033,606176,828SH SOLE 176,82800
ENTERPRISE PRODS PARTNERS LCOM29379210730,7561,135,734SH SOLE 1,135,73400
FIBROCELL SCIENCE INCCOM PAR31572130813,6603,406,545SH SOLE 3,406,54500
FIBROCELL SCIENCE INCCOM PAR3157213088,5562,133,595SH DFND 2,133,59500
HALOZYME THERAPEUTICS INCCOM40637H109247,80519,329,538SH SOLE 19,329,53800
HISTOGENICS CORPCOM43358V1094,8162,690,570SH DFND 2,690,57000
INTREXON CORPCOM46122T1021,504,07162,435,495SH SOLE 62,435,49500
NUSTAR ENERGY LPUNIT COM67058H1026,771145,200SH SOLE 145,20000
ORAGENICS INCCOM NEW6840232033701,000,555SH SOLE 1,000,55500
ORAGENICS INCCOM NEW6840232035,35814,481,089SH DFND 14,481,08900
OVASCIENCE INCCOM69014Q101156100,000SH SOLE 100,00000
OVASCIENCE INCCOM69014Q101426273,224SH DFND 273,22400
PRECIPIO INCCOM74019L1074,911545,639SH SOLE 545,63900
SYNTHETIC BIOLOGICS INCCOM87164U1022,0503,625,000SH SOLE 3,625,00000
SYNTHETIC BIOLOGICS INCCOM87164U1025,4369,613,268SH DFND 9,613,26800
TC PIPELINES LPUT COM LTD PRT87233Q1085,33597,000SH SOLE 97,00000
ZIOPHARM ONCOLOGY INCCOM98973P10160,3949,709,607SH SOLE 9,709,60700