<?xml version="1.0" encoding="UTF-8"?><!-- Generated by Broadridge Transform (tm) - http://www.broadridge.com --><!-- Created: Tue Jun 09 00:53:18 UTC 2026 --><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:common="http://www.sec.gov/edgar/common">
  <schemaVersion>X0202</schemaVersion>
<headerData>
    <submissionType>SCHEDULE 13G</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001304857</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>


    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <securitiesClassTitle>Ordinary Shares</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>06/02/2026</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001541157</issuerCik>
        <issuerName>Akari Therapeutics, Plc.</issuerName>
        <issuerCusips>
          <issuerCusipNumber>00972G405</issuerCusipNumber>
        </issuerCusips>
        <issuerPrincipalExecutiveOfficeAddress>
          <common:street1>401 E. Jackson Street, Suite 3300</common:street1>
          <common:city>Tampa</common:city>
          <common:stateOrCountry>FL</common:stateOrCountry>
          <common:zipCode>33602</common:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(c)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>MMCAP International Inc. SPC</reportingPersonName>
      <citizenshipOrOrganization>E9</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0</soleVotingPower>
        <sharedVotingPower>8000000000</sharedVotingPower>
        <soleDispositivePower>0</soleDispositivePower>
        <sharedDispositivePower>8000000000</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>8000000000</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <classPercent>8.0</classPercent>
      <typeOfReportingPerson>CO</typeOfReportingPerson>
      <comments>The Reporting Person owns 100,000 American Depository Shares (NASDAQ: AXTX) of the Issuer, each convertible into 80,000 Ordinary Shares, par value $0.000000005, of the Issuer</comments>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>MM Asset Management Inc.</reportingPersonName>
      <citizenshipOrOrganization>A6</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0</soleVotingPower>
        <sharedVotingPower>8000000000</sharedVotingPower>
        <soleDispositivePower>0</soleDispositivePower>
        <sharedDispositivePower>8000000000</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>8000000000</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <classPercent>8.0</classPercent>
      <typeOfReportingPerson>CO</typeOfReportingPerson>
      <comments>The Reporting Person owns 100,000 American Depository Shares (NASDAQ: AXTX) of the Issuer, each convertible into 80,000 Ordinary Shares, par value $0.000000005, of the Issuer</comments>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>Akari Therapeutics, Plc.</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>401 E. Jackson Street, Suite 3300, Tampa, FL 33602</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>i) MMCAP International Inc. SPC
ii)  MM Asset Management Inc.</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>i) c/o Mourant Governance Services (Cayman) Limited, 94 Solaris Avenue, Camana Bay, P. O. Box 1348, Grand Cayman KY1-1108, Cayman Islands
ii)  161 Bay Street, TD Canada Trust Tower, Suite 2240, Toronto, Ontario M5J 2S1 Canada</principalBusinessOfficeOrResidenceAddress>
        <citizenship>i) Cayman Islands
ii)  Ontario, Canada</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>Y</notApplicableFlag>
      </item3>
      <item4>
        <amountBeneficiallyOwned>8,000,000,000

Represents 100,000 American Depository Shares, each convertible into 80,000 Ordinary Shares</amountBeneficiallyOwned>
        <classPercent>8.0%

Percent of class calculated on a partially-diluted basis using 91,567,009,533 Ordinary Shares, par value $0.000000005, outstanding as of March 31, 2026, as reported on the Issuer's 10-Q filed with the Securities and Exchange Commission on May 19, 2026.</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>0</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>8,000,000,000</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>0</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>8,000,000,000</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>Y</notApplicableFlag>
      </item5>
      <item6>
        <notApplicableFlag>Y</notApplicableFlag>
      </item6>
      <item7>
        <notApplicableFlag>Y</notApplicableFlag>
      </item7>
      <item8>
        <notApplicableFlag>Y</notApplicableFlag>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>N</notApplicableFlag>
        <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.</certifications>
      </item10>
    </items>
    <exhibitInfo>Exhibit 99.1 Joint Filing Agreement</exhibitInfo>
    <signatureInformation>
      <reportingPersonName>MMCAP International Inc. SPC</reportingPersonName>
      <signatureDetails>
        <signature>Ulla Vestergaard</signature>
        <title>Director</title>
        <date>06/08/2026</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>MM Asset Management Inc.</reportingPersonName>
      <signatureDetails>
        <signature>Hillel Meltz</signature>
        <title>President</title>
        <date>06/08/2026</date>
      </signatureDetails>
    </signatureInformation>
  </formData>

</edgarSubmission>
