ETF SERIES SOLUTIONS

615 East Michigan Street | Milwaukee, Wisconsin 53202

May 2, 2022

VIA EDGAR TRANSMISSION

U.S. Securities and Exchange Commission

Division of Investment Management

100 F Street NE

Washington, DC 20549

Re: ETF Series Solutions (the “Trust”)
File Nos.: 333-179562 and 811-22668

Ladies and Gentlemen:

Pursuant to Rule 497(j) under the Securities Act of 1933, as amended, the Trust on behalf of its series listed in the Appendix below, hereby certifies that the form of Prospectus and Statement of Additional Information that would have been filed under Rule 497(b) or (c) would not have differed from that contained in the most recent amendment dated April 30, 2022, and filed electronically as Post-Effective Amendment No. 795 to the Trust’s Registration Statement on Form N‑1A on April 26, 2022

If you have any questions or require further information, please contact Isabella K. Zoller at (248) 881‑7509 or isabella.zoller@usbank.com.

Sincerely,

/s/ Isabella K. Zoller

Isabella K. Zoller

Secretary

Appendix

Defiance Quantum ETF (S000062478)

Defiance Next Gen Connectivity ETF (S000064804)

Defiance Next Gen SPAC Derived ETF (S000062479)

Defiance Next Gen H2 ETF (S000071206)

Defiance Next Gen Altered Experience ETF (S000071901)

Defiance Hotel, Airline, and Cruise ETF (S000072009)

Defiance Digital Revolution ETF (S000072573)

Defiance Indxx Junior Semiconductor ETF (S000064807)

Defiance Next Gen Conductivity ETF (S000072574)