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  <schemaVersion>X0202</schemaVersion>
<headerData>
    <submissionType>SCHEDULE 13G</submissionType>
	    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001388325</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>





    </filerInfo>
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    <coverPageHeader>
	      <securitiesClassTitle>Voting Common Stock, par value $0.001 per share</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>06/30/2026</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001540171</issuerCik>        <issuerName>Avalyn Pharma Inc. </issuerName>

    <issuerCusips>
					<issuerCusipNumber>05348Y105</issuerCusipNumber>
				</issuerCusips>

        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>105 W First Street</com:street1>
                    <com:city>Boston</com:city>
          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>02127</com:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>

	        <designateRulesPursuantThisScheduleFiled>
	           <designateRulePursuantThisScheduleFiled>Rule 13d-1(d)</designateRulePursuantThisScheduleFiled>
						      </designateRulesPursuantThisScheduleFiled>

    </coverPageHeader>

	    <coverPageHeaderReportingPersonDetails>




    <reportingPersonName>Novo Holdings A/S</reportingPersonName>



		 <citizenshipOrOrganization>G7</citizenshipOrOrganization>

      <reportingPersonBeneficiallyOwnedNumberOfShares>
                <soleVotingPower>3883289.00</soleVotingPower>
                          <sharedVotingPower>0.00</sharedVotingPower>
                          <soleDispositivePower>3883289.00</soleDispositivePower>
                         <sharedDispositivePower>0.00</sharedDispositivePower>
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              <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>3883289.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>


     	    <classPercent>8.8</classPercent>









	        <typeOfReportingPerson>CO</typeOfReportingPerson>





    </coverPageHeaderReportingPersonDetails>

    <items>
      <item1>
        <issuerName>Avalyn Pharma Inc. </issuerName>
        <issuerPrincipalExecutiveOfficeAddress>105 W First Street, Boston, MA, 02127.</issuerPrincipalExecutiveOfficeAddress>
      </item1>

      <item2>
        <filingPersonName>Novo Holdings A/S, a Danish corporation, is an investment firm focused on life sciences and finance that is wholly owned by Novo Nordisk Foundation (the "Foundation"), a Danish commercial foundation. Novo Holdings A/S is the holding company in the group of Novo companies, currently comprised of Novo Nordisk A/S and Novonesis A/S, and is responsible for managing the Foundation's assets, including its financial assets.  Based on the governance structure of Novo Holdings A/S and the Foundation, the Foundation is not deemed to have any beneficial ownership of the securities of the Issuer held by Novo Holdings A/S.</filingPersonName>        <principalBusinessOfficeOrResidenceAddress>Tuborg Havnevej 19
 2900 Hellerup, Denmark</principalBusinessOfficeOrResidenceAddress>        <citizenship>Denmark</citizenship>      </item2>

        <item3>
		        <notApplicableFlag>Y</notApplicableFlag>

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    <item4>
    <amountBeneficiallyOwned>3,883,289</amountBeneficiallyOwned>    <classPercent>8.8%</classPercent>
      <numberOfSharesPersonHas>
        <solePowerOrDirectToVote>3,883,289</solePowerOrDirectToVote>
        <sharedPowerOrDirectToVote>0</sharedPowerOrDirectToVote>
        <solePowerOrDirectToDispose>3,883,289</solePowerOrDirectToDispose>
        <sharedPowerOrDirectToDispose>0</sharedPowerOrDirectToDispose>
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        <item5>
	          <notApplicableFlag>Y</notApplicableFlag>


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        <item6>
	  	  <notApplicableFlag>Y</notApplicableFlag>
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        <item7>
	  	  <notApplicableFlag>Y</notApplicableFlag>


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          <item8>
                <notApplicableFlag>Y</notApplicableFlag>

              </item8>


            <item9>
                <notApplicableFlag>Y</notApplicableFlag>
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      <item10>
                    <notApplicableFlag>Y</notApplicableFlag>

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    </items>


	    <signatureInformation>
      <reportingPersonName>Novo Holdings A/S</reportingPersonName>

      <signatureDetails>
        <signature>Barbara Fiorini</signature>
        <title>Barbara Fiorini, General Counsel, Finance &amp; Operations</title>
        <date>08/14/2026</date>
      </signatureDetails>

    </signatureInformation>



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