X0306 4 2022-11-02 0001540159 Edesa Biotech, Inc. EDSA 0001620146 NIFFENEGGER KATHI C/O EDESA BIOTECH, INC. 100 SPY COURT MARKHAM A6 L3R 5H6 ONTARIO, CANADA true Chief Financial Officer Common Shares 2022-11-02 4 A false 8888 1.125 A 10715 I By Trust Common Share Warrants (Right to Buy) 1.50 2022-11-02 4 A false 4444 A Common Shares 4444 4444 I By Trust Common Share Warrants (Right to Buy) 1.00 2022-11-02 4 A false 4444 A Common Shares 4444 4444 I By Trust The reported securities are included within 8,888 Common Shares purchased by the reporting person for $1.1250 per Common Share. Each Common Share includes the purchase of one-half of a Class A Warrant to purchase one Common Share, and one-half of a Class B Warrant to purchase one Common Share. Consists of Class A Warrants to purchase Common Shares. The Class A Warrants are exercisable on the date that is the earlier to occur of 60 days from the closing date of the offering and the date a Registration Statement covering the resale of the Common Shares and Common Shares issuable upon exercise of the Warrants is declared effective (the "Initial Exercise Date") and will expire three years after the Initial Exercise Date. Consists of Class B Warrants to purchase Common Shares. The Class B Warrants are exercisable on the Initial Exercise Date and will expire 12 months after the Initial Exercise Date. /s/ Kathi Niffenegger 2022-11-04