144 0001888075 XXXXXXXX LIVE 0001534969 Sera Prognostics, Inc. 001-40606 2749 East Parleys Way Suite 200 Salt Lake City UT 84109 (801)-990-0520 Kearney Paul Officer Class A Common Morgan Stanley Smith Barney LLC

1 New York Plaza 38th Floor New York NY 10004

1338 5571 33772500 03/06/2025 NASDAQ Class A Common 03/06/2025 Restricted Stock Unit Vesting Issuer N 1338 03/06/2025 Not Applicable N Paul Kearney

2749 E. Parleys Way Suite 200 Salt Lake City UT 84109

Class A Common 01/10/2025 13419 99581 Paul Kearney

2749 E. Parleys Way Suite 200 Salt Lake City UT 84109

Class A Common 02/12/2025 5342 24444 The sale on this form represents the number of shares sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. The sale is mandated by the Issuer's election to require the satisfaction of tax withholding obligations to be funded by sell to cover transactions and does not represent a discretionary transaction by the Reporting Person. 03/07/2025 /s/ Paul Kearney