Stock-Based Compensation - Schedule of Stock Option Activity (Details) - $ / shares	3 Months Ended		12 Months Ended
	Mar. 31, 2017		Dec. 31, 2016		Dec. 31, 2015
Number of Options Outstanding, Beginning Balance	173,750
Number of Options Outstanding, Granted	111,667	[1]	142,500
Number of Options Outstanding, Exercised
Number of Options Outstanding, Canceled			(5,417)
Number of Options Outstanding, Ending Balance	285,417		173,750
Number of Options Exercisable, Ending Balance	86,285
Weighted- Average Exercise Price Options Outstanding, Beginning Balance	$ 9.24
Weighted- Average Exercise Price Options Outstanding, Granted	4.71
Weighted- Average Exercise Price Options Outstanding, Exercised
Weighted- Average Exercise Price Options Outstanding, Ending Balance	7.47		$ 9.24
Weighted- Average Exercise Price Options Exercisable, Ending Balance	$ 11.79
Stock Option [Member]
Number of Options Outstanding, Beginning Balance	173,750		36,667		16,667	[2]
Number of Options Outstanding, Granted			142,500	[3]	27,500	[4]
Number of Options Outstanding, Exercised
Number of Options Outstanding, Canceled			(5,417)	[3]	(7,500)	[4]
Number of Options Outstanding, Ending Balance			173,750		36,667
Number of Options Exercisable, Ending Balance			48,325
Weighted- Average Exercise Price Options Outstanding, Beginning Balance	$ 9.24		$ 38.40		$ 24.00
Weighted- Average Exercise Price Options Outstanding, Granted			5.49		69.60
Weighted- Average Exercise Price Options Outstanding, Exercised
Weighted- Average Exercise Price Options Outstanding, Canceled			108.69		120.00
Weighted- Average Exercise Price Options Outstanding, Ending Balance			9.24		$ 38.40
Weighted- Average Exercise Price Options Exercisable, Ending Balance			$ 14.31

[1] Options granted under 2016 Stock Incentive Plan

[2] Non-Plan options.

[3] 142,500 options granted under 2016 Equity Incentive Plan; 5,417 options were canceled under the 2015 Stock Incentive Plan.

[4] 27,500 options granted under 2015 Stock Incentive Plan; 7,500 non-plan options, which were subsequently canceled under an agreement with the holder.