<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
  <schemaVersion>X0202</schemaVersion>
<headerData>
    <submissionType>SCHEDULE 13G</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0002103370</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <securitiesClassTitle>Common Stock, $0.001 par value per share</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>09/16/2026</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001534525</issuerCik>
        <issuerName>Xenetic Biosciences, Inc.</issuerName>
        <issuerCusips>
          <issuerCusipNumber>984015602</issuerCusipNumber>
        </issuerCusips>
        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>945 CONCORD ST.</com:street1>
          <com:city>FRAMINGHAM</com:city>
          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>01701</com:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(c)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>MJL Manager LLC</reportingPersonName>
      <memberGroup>b</memberGroup>
      <citizenshipOrOrganization>X1</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>0.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>0.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>0.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <classPercent>0.0</classPercent>
      <typeOfReportingPerson>IA</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>Michael Liu</reportingPersonName>
      <memberGroup>b</memberGroup>
      <citizenshipOrOrganization>X1</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>0.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>0.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>0.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <classPercent>0.0</classPercent>
      <typeOfReportingPerson>IN</typeOfReportingPerson>
      <comments>Michael Liu is the sole control person of MJL Manager LLC ("MJL") and, in such capacity, has the authority to direct the voting and disposition of the shares held in discretionary accounts managed by MJL. The reporting of shared power by both reporting persons shall not be construed as an admission that either is the beneficial owner of shares beneficially owned by the other, and each expressly disclaims beneficial ownership except to the extent of such person's actual pecuniary interest therein.</comments>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>Xenetic Biosciences, Inc.</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>945 CONCORD ST., FRAMINGHAM, MASSACHUSETTS, 01701</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>MJL Manager LLC
Michael Liu</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>12 Manley Road, Pennington NJ 08534</principalBusinessOfficeOrResidenceAddress>
        <citizenship>MJL Manager LLC - New Jersey
Michael Liu - USA</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>Y</notApplicableFlag>
      </item3>
      <item4>
        <amountBeneficiallyOwned>MJL Manager LLC - 0
Michael Liu - 0</amountBeneficiallyOwned>
        <classPercent>MJL Manager LLC - 0%
Michael Liu - 0%</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>MJL Manager LLC - 0
Michael Liu - 0</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>MJL Manager LLC - 0
Michael Liu - 0</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>MJL Manager LLC - 0
Michael Liu - 0</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>MJL Manager LLC - 0
Michael Liu - 0</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>N</notApplicableFlag>
        <classOwnership5PercentOrLess>Y</classOwnership5PercentOrLess>
      </item5>
      <item6>
        <notApplicableFlag>Y</notApplicableFlag>
      </item6>
      <item7>
        <notApplicableFlag>Y</notApplicableFlag>
      </item7>
      <item8>
        <notApplicableFlag>N</notApplicableFlag>
        <identificationAndClassificationOfGroupMembers>See Item 2(a) in lieu of an Exhibit.</identificationAndClassificationOfGroupMembers>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>N</notApplicableFlag>
        <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under &amp;#167; 240.14a-11.

</certifications>
      </item10>
    </items>
    <signatureInformation>
      <reportingPersonName>MJL Manager LLC</reportingPersonName>
      <signatureDetails>
        <signature>Michael Liu</signature>
        <title>Managing Member</title>
        <date>09/18/2026</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Michael Liu</reportingPersonName>
      <signatureDetails>
        <signature>Michael Liu</signature>
        <title>Individual</title>
        <date>09/18/2026</date>
      </signatureDetails>
    </signatureInformation>
  </formData>

</edgarSubmission>
