144 0001534265 XXXXXXXX LIVE 0000834365 BioLife Solutions, Inc. 001-36362 3303 Monte Villa Parkway Suite 310 Bothell WA 98021 425-402-1400 Casdin Partners Master Fund, L.P. 10% Shareholder Common Stock, par value $0.001 per share TD SECURITIES (USA) LLC

125 Park Avenue 20th Floor New York NY 10017

750000 21410325.00 47905265 10/15/2025 NASDAQ Common Stock, par value $0.001 per share 11/20/2019 Purchase The shares were purchased in the open market. N 9417 11/20/2019 Cash Common Stock, par value $0.001 per share 07/02/2020 Purchase The shares were purchased directly from the issuer. N 435000 07/02/2020 Cash Common Stock, par value $0.001 per share 07/10/2020 Purchase The shares were purchased directly from a shareholder of the issuer. N 305583 07/10/2020 Cash N Casdin Partners Master Fund, L.P.

1350 Avenue of the Americas Suite 2600 New York NY 10019

Common Stock, par value $0.001 per share 08/15/2025 500000 12200000.00 Casdin Partners Master Fund, L.P.

1350 Avenue of the Americas Suite 2600 New York NY 10019

Common Stock, par value $0.001 per share 08/11/2025 500000 11300000.00 10/15/2025 /s/ Eli Casdin