The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| 4D MOLECULAR THERAPEUTICS IN | COM | 35104E100 | 43,178 | 995,354 | SH | SOLE | 0 | 995,354 | 0 | ||
| 908 DEVICES INC | COM | 65443P102 | 19,715 | 406,502 | SH | SOLE | 0 | 406,502 | 0 | ||
| ADAPTIVE BIOTECHNOLOGIES COR | COM | 00650F109 | 46,299 | 1,150,000 | SH | SOLE | 0 | 1,150,000 | 0 | ||
| ADVERUM BIOTECHNOLOGIES INC | COM | 00773U108 | 21,807 | 2,211,622 | SH | SOLE | 0 | 2,211,622 | 0 | ||
| AGIOS PHARMACEUTICALS INC | COM | 00847X104 | 111,801 | 2,165,000 | SH | SOLE | 0 | 2,165,000 | 0 | ||
| ALECTOR INC | COM | 014442107 | 33,231 | 1,650,000 | SH | SOLE | 0 | 1,650,000 | 0 | ||
| ALLOGENE THERAPEUTICS INC | COM | 019770106 | 45,890 | 1,300,000 | SH | SOLE | 0 | 1,300,000 | 0 | ||
| ALNYLAM PHARMACEUTICALS INC | COM | 02043Q107 | 124,247 | 880,000 | SH | SOLE | 0 | 880,000 | 0 | ||
| BEAM THERAPEUTICS INC | COM | 07373V105 | 65,538 | 818,820 | SH | SOLE | 0 | 818,820 | 0 | ||
| BEIGENE LTD | SPONSORED ADR | 07725L102 | 52,212 | 150,000 | SH | SOLE | 0 | 150,000 | 0 | ||
| BERKELEY LTS INC | COM | 084310101 | 10,046 | 200,000 | SH | SOLE | 0 | 200,000 | 0 | ||
| BIOLIFE SOLUTIONS INC | COM NEW | 09062W204 | 267,844 | 7,440,107 | SH | SOLE | 0 | 7,440,107 | 0 | ||
| BLUEPRINT MEDICINES CORP | COM | 09627Y109 | 150,707 | 1,550,000 | SH | SOLE | 0 | 1,550,000 | 0 | ||
| BURNING ROCK BIOTECH LTD | SPONSORED ADR | 12233L107 | 22,805 | 847,150 | SH | SOLE | 0 | 847,150 | 0 | ||
| CAREDX INC | COM | 14167L103 | 81,254 | 1,193,335 | SH | SOLE | 0 | 1,193,335 | 0 | ||
| CLOVER HEALTH INVESTMENTS CO | COM CL A | 18914F103 | 5,492 | 726,511 | SH | SOLE | 0 | 726,511 | 0 | ||
| CODEXIS INC | COM | 192005106 | 99,114 | 4,330,000 | SH | SOLE | 0 | 4,330,000 | 0 | ||
| CODIAK BIOSCIENCES INC | COM | 192010106 | 1,156 | 76,688 | SH | SOLE | 0 | 76,688 | 0 | ||
| CONSTELLATION PHARMCETICLS I | COM | 210373106 | 42,102 | 1,800,000 | SH | SOLE | 0 | 1,800,000 | 0 | ||
| CRISPR THERAPEUTICS AG | NAMEN AKT | H17182108 | 32,464 | 266,430 | SH | SOLE | 0 | 266,430 | 0 | ||
| DECIBEL THERAPEUTICS INC | COM | 24343R106 | 13,023 | 1,146,421 | SH | SOLE | 0 | 1,146,421 | 0 | ||
| DENALI THERAPEUTICS INC | COM | 24823R105 | 91,931 | 1,610,000 | SH | SOLE | 0 | 1,610,000 | 0 | ||
| DERMTECH INC | COM | 24984K105 | 88,629 | 1,745,000 | SH | SOLE | 0 | 1,745,000 | 0 | ||
| DYNE THERAPEUTICS INC | COM | 26818M108 | 9,473 | 610,000 | SH | SOLE | 0 | 610,000 | 0 | ||
| EXACT SCIENCES CORP | COM | 30063P105 | 311,025 | 2,360,186 | SH | SOLE | 0 | 2,360,186 | 0 | ||
| FATE THERAPEUTICS INC | COM | 31189P102 | 280,330 | 3,400,000 | SH | SOLE | 0 | 3,400,000 | 0 | ||
| FOGHORN THERAPEUTICS INC | COM | 344174107 | 2,850 | 216,216 | SH | SOLE | 0 | 216,216 | 0 | ||
| FULCRUM THERAPEUTICS INC | COM | 359616109 | 14,621 | 1,241,176 | SH | SOLE | 0 | 1,241,176 | 0 | ||
| GENERATION BIO CO | COM | 37148K100 | 45,855 | 1,611,214 | SH | SOLE | 0 | 1,611,214 | 0 | ||
| GLOBAL BLOOD THERAPEUTICS IN | COM | 37890U108 | 36,675 | 900,000 | SH | SOLE | 0 | 900,000 | 0 | ||
| INVITAE CORP | COM | 46185L103 | 466,302 | 12,203,669 | SH | SOLE | 0 | 12,203,669 | 0 | ||
| KRONOS BIO INC | COM | 50107A104 | 17,077 | 583,436 | SH | SOLE | 0 | 583,436 | 0 | ||
| MAGENTA THERAPEUTICS INC | COM | 55910K108 | 39,617 | 3,346,034 | SH | SOLE | 0 | 3,346,034 | 0 | ||
| ORCHARD THERAPEUTICS PLC | ADS | 68570P101 | 23,344 | 3,215,434 | SH | SOLE | 0 | 3,215,434 | 0 | ||
| ORIC PHARMACEUTICALS INC | COM | 68622P109 | 14,737 | 601,515 | SH | SOLE | 0 | 601,515 | 0 | ||
| PACIFIC BIOSCIENCES CALIF IN | COM | 69404D108 | 166,550 | 5,000,000 | SH | SOLE | 0 | 5,000,000 | 0 | ||
| RELAY THERAPEUTICS INC | COM | 75943R102 | 116,676 | 3,375,058 | SH | SOLE | 0 | 3,375,058 | 0 | ||
| REVOLUTION MEDICINES INC | COM | 76155X100 | 84,627 | 1,844,535 | SH | SOLE | 0 | 1,844,535 | 0 | ||
| SANA BIOTECHNOLOGY INC | COM | 799566104 | 2,008 | 60,000 | SH | SOLE | 0 | 60,000 | 0 | ||
| SANGAMO THERAPEUTICS INC | COM | 800677106 | 6,892 | 550,000 | SH | SOLE | 0 | 550,000 | 0 | ||
| SAREPTA THERAPEUTICS INC | COM | 803607100 | 40,992 | 550,000 | SH | SOLE | 0 | 550,000 | 0 | ||
| SEER INC | COM CL A | 81578P106 | 7,503 | 150,000 | SH | SOLE | 0 | 150,000 | 0 | ||
| STOKE THERAPEUTICS INC | COM | 86150R107 | 4,661 | 120,000 | SH | SOLE | 0 | 120,000 | 0 | ||
| SYNDAX PHARMACEUTICALS INC | COM | 87164F105 | 22,360 | 1,000,000 | SH | SOLE | 0 | 1,000,000 | 0 | ||
| TAYSHA GENE THERAPIES INC | COM SHS | 877619106 | 16,655 | 820,440 | SH | SOLE | 0 | 820,440 | 0 | ||
| TURNING POINT THERAPEUTICS I | COM | 90041T108 | 7,094 | 75,000 | SH | SOLE | 0 | 75,000 | 0 | ||
| TWIST BIOSCIENCE CORP | COM | 90184D100 | 123,860 | 1,000,000 | SH | SOLE | 0 | 1,000,000 | 0 | ||
| ZAI LAB LTD | ADR | 98887Q104 | 25,352 | 190,000 | SH | SOLE | 0 | 190,000 | 0 | ||